In a negligence action filed under the Federal Employer's Liability Act (FELA) and the Federal Safety Appliance Act (SAA), grant of a directed verdict in favor of defendant-railroad is affirmed where: 1) FELA liability cannot be premised on a violation of the SAA, since, as a matter of law, the SAA and its regulations did not prohibit the use of vertical handholds on a railcar in combination with horizontal handholds; and 2) directed verdict for defendant was proper as substantial evidence in the record did not support a basis, independent of the SAA, for the negligence claim.